League Leaders - Offense
| Passing Yards | Complete List | |
Logan Norris
|
1. Logan Norris, MIA | 695 |
| 2. Nick Townsend, SF | 559 | |
| 3. Dom Heyward, GB | 338 | |
| 4. Peter Carroll, LAR | 188 | |
| 5. Drew James, SEA | 168 | |
| Rushing Yards | Complete List | |
Steven Wroten
|
1. Steven Wroten, MIA | 123 |
| 2. Randy Blanton, KC | 80 | |
| 3. Jeff Burke, LAR | 78 | |
| 4. Terron Rossum, NO | 50 | |
| 5. Quincy Woodley, CAR | 38 | |
| Receiving Yards | Complete List | |
Manny Benford
|
1. Manny Benford, SF | 399 |
| 2. A.J. Stinson, LAC | 246 | |
| 3. DeMarcus Whitfield, SEA | 176 | |
| 4. Tyler Woodard, HOU | 160 | |
| 5. Timmy Harrell, IND | 139 | |
League Leaders - Defense
| Tackles | Complete List | |
Nate Drayton
|
1. Nate Drayton, PIT | 7 |
| 2. Michael Turner, TB | 6 | |
| 3. Jose Burch, PIT | 6 | |
| 4. Reggie McLean, MIA | 6 | |
| 5. Trevor Jones, NYG | 5 | |
| Sacks | Complete List | |
Jose Burch
|
1. Jose Burch, PIT | 2 |
| 2. Brian Allen, ARI | 2 | |
| 3. Jae Mathis, ARI | 2 | |
| 4. Phillip Childs, PHI | 1 | |
| 5. Eddie Harris, JAX | 1 | |
| Interceptions | Complete List | |
Justin Poole
|
1. Justin Poole, SF | 2 |
| 2. Derek Bass, BAL | 2 | |
| 3. Phillip Childs, PHI | 1 | |
| 4. Michael McMillan, PHI | 1 | |
| 5. Nicholas Medlock, ARI | 1 | |