League Leaders - Offense
| Passing Yards | Complete List | |
Dalton Purcell
|
1. Dalton Purcell, TB | 1890 |
| 2. Deangelo Kemper, LV | 1115 | |
| 3. Noah Wagner, LAR | 892 | |
| 4. Irving Williamson, NYG | 90 | |
| 5. Milton Gonzales, MIA | 1 | |
| Rushing Yards | Complete List | |
Brennon Young
|
1. Brennon Young, NE | 514 |
| 2. Justice Haynes, LAR | 211 | |
| 3. Tevin Sharron, MIA | 164 | |
| 4. TreVonte Citizen, SF | 146 | |
| 5. Javin Atherholt, DET | 108 | |
| Receiving Yards | Complete List | |
Skye Cottrell
|
1. Skye Cottrell, CHI | 447 |
| 2. Abhinav Cullom, ARI | 333 | |
| 3. Kaleb Marchetti, MIA | 311 | |
| 4. Andre Macintyre, NYJ | 303 | |
| 5. Jalen Rosher, PIT | 270 | |
League Leaders - Defense
| Tackles | Complete List | |
Henri Etzold
|
1. Henri Etzold, WAS | 33 |
| 2. Deontae Okumuringa, PIT | 31 | |
| 3. Keith Viinanen, CAR | 27 | |
| 4. Sekandi Kingsland, TEN | 25 | |
| 5. Jonathan York, SF | 22 | |
| Sacks | Complete List | |
Ingimar Cyrusdottir
|
1. Ingimar Cyrusdottir, MIN | 8 |
| 2. Dani Horne, PHI | 4 | |
| 3. Phumzile Nair, LV | 4 | |
| 4. Pangeran Mustofa, ARI | 4 | |
| 5. Nonhlanhla De Villiers, SEA | 3 | |
| Interceptions | Complete List | |
Jay Hudson
|
1. Jay Hudson, TEN | 3 |
| 2. Alexander Collins, IND | 2 | |
| 3. Frederic Christensen, NE | 2 | |
| 4. Duncan Woods, HOU | 2 | |
| 5. Rio Vincent, BUF | 2 | |