League Leaders - Offense
| Passing Yards | Complete List | |
Jordan Love
|
1. Jordan Love, GB | 3989 |
| 2. Carson Wentz, PHI | 3936 | |
| 3. Patrick Mahomes, KC | 3906 | |
| 4. Jalen Hurts, DEN | 3695 | |
| 5. Jayden Daniels, TB | 3683 | |
| Rushing Yards | Complete List | |
Dalvin Cook
|
1. Dalvin Cook, DEN | 1235 |
| 2. Nick Chubb, CLE | 1233 | |
| 3. Saquon Barkley, NYG | 1211 | |
| 4. Aaron Jones, GB | 1150 | |
| 5. Alvin Kamara, NO | 1063 | |
| Receiving Yards | Complete List | |
Robby Anderson
|
1. Robby Anderson, PHI | 1611 |
| 2. Davante Adams, GB | 1555 | |
| 3. D.J. Chark Jr, NE | 1502 | |
| 4. Terry McLaurin, WAS | 1376 | |
| 5. John Ross III, CIN | 1180 | |
League Leaders - Defense
| Tackles | Complete List | |
Chazz Surratt
|
1. Chazz Surratt, LAR | 67 |
| 2. Bobby Wagner, SEA | 62 | |
| 3. Foyesade Oluokun, MIA | 62 | |
| 4. Eric Kendricks, MIN | 61 | |
| 5. Tanner Muse, LV | 61 | |
| Sacks | Complete List | |
Cory Durden
|
1. Cory Durden, PHI | 15 |
| 2. Shaquil Barrett, TB | 15 | |
| 3. Montez Sweat, WAS | 14 | |
| 4. Myles Garrett, CLE | 14 | |
| 5. Chandler Jones, BUF | 13 | |
| Interceptions | Complete List | |
Davion Taylor
|
1. Davion Taylor, PHI | 14 |
| 2. Darnell Savage, GB | 10 | |
| 3. Denzel Ward, CLE | 10 | |
| 4. Avonte Maddox, PHI | 9 | |
| 5. Darius Slay Jr, PHI | 9 | |