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Defensive Leaders
| Passing | Cmp | Att | Yds | TD |
| Lamar Jackson | 328 | 472 | 8342 | 92 |
| Drew Brees | 374 | 540 | 7657 | 76 |
| Randall Cunningham | 354 | 553 | 6961 | 61 |
| Joe Montana | 360 | 515 | 6478 | 71 |
| Tom Brady | 345 | 496 | 6305 | 45 |
| Rushing | Att | Yds | Avg | TD |
| Bo Jackson | 494 | 3616 | 7.3 | 46 |
| Adrian Peterson | 413 | 3505 | 8.5 | 37 |
| Curtis Martin | 278 | 1832 | 6.6 | 19 |
| Arian Foster | 279 | 1701 | 6.1 | 24 |
| Eric Dickerson | 282 | 1682 | 6.0 | 15 |
| Receiving | Rec | Yds | Avg | TD |
| Andre Johnson | 91 | 2624 | 28.8 | 40 |
| Parris Campbell | 96 | 2603 | 27.1 | 24 |
| Mike Evans | 88 | 2322 | 26.4 | 15 |
| Ja'Marr Chase | 98 | 2288 | 23.3 | 21 |
| Devin Hester | 95 | 2265 | 23.8 | 23 |
| Tackles | TAK | SCK | FF | INTS |
| Myles Jack | 87 | 2 | 1 | 0 |
| Deion Jones | 78 | 2 | 1 | 3 |
| Darrell Green | 70 | 0 | 1 | 11 |
| Fred Warner | 69 | 0 | 0 | 7 |
| Leighton Vander Esch | 69 | 4 | 3 | 0 |
| Interceptions | INTS | TAK | SCK | FF |
| Denzel Ward | 12 | 29 | 0 | 0 |
| Darrell Green | 11 | 70 | 0 | 1 |
| Rod Woodson | 11 | 40 | 0 | 1 |
| Kam Chancellor | 11 | 56 | 0 | 1 |
| Deion Sanders | 10 | 46 | 0 | 0 |
| Sacks | SCK | TAK | FF | INTS |
| Lawrence Taylor | 20 | 44 | 0 | 0 |
| Jadeveon Clowney | 17 | 34 | 2 | 1 |
| Nick Bosa | 16 | 31 | 0 | 1 |
| Roquan Smith | 14 | 23 | 1 | 1 |
| A.J. Epenesa | 14 | 26 | 0 | 0 |
| INT Thrown | Cmp | Att | Yds | Int |
| Randall Cunningham | 354 | 553 | 6961 | 43 |
| Otto Graham | 272 | 431 | 5037 | 42 |
| Joe Namath | 243 | 374 | 4097 | 41 |
| Trevor Lawrence | 239 | 378 | 3771 | 41 |
| Peyton Manning | 254 | 441 | 3699 | 40 |
| AFC East | W | L | T | Pct |
| Miami Dolphins | 10 | 5 | 0 | 0.667 |
| New England Patriots | 8 | 7 | 0 | 0.533 |
| Buffalo Bills | 7 | 8 | 0 | 0.467 |
| New York Jets | 1 | 15 | 0 | 0.063 |
| AFC West | W | L | T | Pct |
| Los Angeles Chargers | 12 | 3 | 0 | 0.800 |
| Kansas City Chiefs | 11 | 5 | 0 | 0.688 |
| Las Vegas Raiders | 8 | 7 | 0 | 0.533 |
| Denver Broncos | 5 | 10 | 0 | 0.333 |
| AFC North | W | L | T | Pct |
| Cincinnati Bengals | 9 | 7 | 0 | 0.563 |
| Baltimore Ravens | 5 | 10 | 0 | 0.333 |
| Pittsburgh Steelers | 4 | 11 | 0 | 0.267 |
| Cleveland Browns | 3 | 12 | 0 | 0.200 |
| AFC South | W | L | T | Pct |
| Tennessee Titans | 12 | 3 | 0 | 0.800 |
| Houston Texans | 12 | 4 | 0 | 0.750 |
| Jacksonville Jaguars | 8 | 7 | 0 | 0.533 |
| Indianapolis Colts | 5 | 10 | 0 | 0.333 |
| NFC East | W | L | T | Pct |
| Philadelphia Eagles | 14 | 2 | 0 | 0.875 |
| Dallas Cowboys | 11 | 4 | 0 | 0.733 |
| Washington Football Team | 5 | 11 | 0 | 0.313 |
| New York Giants | 1 | 14 | 0 | 0.067 |
| NFC West | W | L | T | Pct |
| Seattle Seahawks | 11 | 4 | 0 | 0.733 |
| San Francisco 49ers | 9 | 7 | 0 | 0.563 |
| Arizona Cardinals | 8 | 7 | 0 | 0.533 |
| Los Angeles Rams | 3 | 12 | 0 | 0.200 |
| NFC North | W | L | T | Pct |
| Detroit Lions | 12 | 3 | 0 | 0.800 |
| Green Bay Packers | 8 | 7 | 0 | 0.533 |
| Chicago Bears | 8 | 7 | 0 | 0.533 |
| Minnesota Vikings | 5 | 10 | 0 | 0.333 |
| NFC South | W | L | T | Pct |
| New Orleans Saints | 9 | 6 | 0 | 0.600 |
| Atlanta Falcons | 7 | 8 | 0 | 0.467 |
| Carolina Panthers | 7 | 8 | 0 | 0.467 |
| Tampa Bay Buccaneers | 6 | 10 | 0 | 0.375 |
On The Bubble
On The Bubble
| Ravens Signed ROLB Brian Burns 88 OVR |
| Cowboys Signed SS Tevaughn Campbell 65 OVR |
| Cowboys Signed RE Maxx Crosby 81 OVR |
| Lions Signed WR T.Y. Hilton 84 OVR |
| Jaguars Signed TE Andrew Vollert 55 OVR |
| Cowboys Signed CB Greedy Williams 79 OVR |
| Lions Signed FS Sean Taylor 99 OVR |
| Cowboys Signed WR Antonio Brown 88 OVR |
| Jaguars Released DT Morgan Fox 74 OVR |
| Bears Signed CB Simeon Thomas 64 OVR |
0
10-5-0
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12-3-0
2021 - Season - Week 17