League Leaders - Offense
| Passing Yards | Complete List | |
Sam Howell
|
1. Sam Howell, WAS | 3973 |
| 2. Matt Corral, CAR | 569 | |
| 3. Malik Willis, TEN | 85 | |
| 4. Carson Strong, PHI | 36 | |
| 5. Bailey Zappe, NE | 10 | |
| Rushing Yards | Complete List | |
Breece Hall
|
1. Breece Hall, NYJ | 1200 |
| 2. Dameon Pierce, HOU | 878 | |
| 3. Kenneth Walker III, SEA | 599 | |
| 4. Brian Robinson Jr, WAS | 405 | |
| 5. Isaiah Spiller, LAC | 237 | |
| Receiving Yards | Complete List | |
Garrett Wilson
|
1. Garrett Wilson, NYJ | 1576 |
| 2. John Metchie III, HOU | 1471 | |
| 3. Jameson Williams, DET | 1463 | |
| 4. Jahan Dotson, WAS | 1073 | |
| 5. George Pickens, PIT | 822 | |
League Leaders - Defense
| Tackles | Complete List | |
Quay Walker
|
1. Quay Walker, GB | 83 |
| 2. Andrew Booth Jr, MIN | 62 | |
| 3. Daxton Hill, CIN | 62 | |
| 4. Brian Asamoah II, MIN | 58 | |
| 5. Christian Harris, HOU | 55 | |
| Sacks | Complete List | |
Arnold Ebiketie
|
1. Arnold Ebiketie, ATL | 5 |
| 2. Aidan Hutchinson, DET | 5 | |
| 3. Travon Walker, JAX | 5 | |
| 4. Christian Harris, HOU | 5 | |
| 5. Kayvon Thibodeaux, NYG | 5 | |
| Interceptions | Complete List | |
Christian Harris
|
1. Christian Harris, HOU | 9 |
| 2. Sauce Gardner, NYJ | 9 | |
| 3. Tariq Woolen, HOU | 7 | |
| 4. Kyle Hamilton, BAL | 4 | |
| 5. Dane Belton, NYG | 4 | |