League Leaders - Offense
| Passing Yards | Complete List | |
Sam Howell
|
1. Sam Howell, WAS | 3967 |
| 2. Brock Purdy, SF | 3259 | |
| 3. Kenny Pickett, PIT | 3077 | |
| 4. Matt Corral, CAR | 3024 | |
| 5. Desmond Ridder, ATL | 73 | |
| Rushing Yards | Complete List | |
Dameon Pierce
|
1. Dameon Pierce, HOU | 1247 |
| 2. Isiah Pacheco, KC | 869 | |
| 3. Brian Robinson Jr, WAS | 841 | |
| 4. Breece Hall, NYJ | 748 | |
| 5. Kenneth Walker III, SEA | 654 | |
| Receiving Yards | Complete List | |
John Metchie III
|
1. John Metchie III, HOU | 1089 |
| 2. Chris Olave, NO | 1052 | |
| 3. Christian Watson, GB | 1009 | |
| 4. Jahan Dotson, WAS | 920 | |
| 5. Drake London, ATL | 911 | |
League Leaders - Defense
| Tackles | Complete List | |
Quay Walker
|
1. Quay Walker, GB | 74 |
| 2. Christian Harris, HOU | 72 | |
| 3. Devin Lloyd, JAX | 71 | |
| 4. Daxton Hill, CIN | 58 | |
| 5. Travon Walker, JAX | 55 | |
| Sacks | Complete List | |
Kayvon Thibodeaux
|
1. Kayvon Thibodeaux, NYG | 14 |
| 2. Arnold Ebiketie, ATL | 6 | |
| 3. Travon Walker, JAX | 4 | |
| 4. Micah McFadden, NYG | 3 | |
| 5. Dominique Robinson, CHI | 2 | |
| Interceptions | Complete List | |
Nakobe Dean
|
1. Nakobe Dean, PHI | 7 |
| 2. Nazeeh Johnson, PHI | 5 | |
| 3. Dane Belton, NYG | 5 | |
| 4. Trent McDuffie, KC | 4 | |
| 5. Kyle Hamilton, BAL | 4 | |