League Leaders - Offense
| Passing Yards | Complete List | |
Johnathan Hartwig
|
1. Johnathan Hartwig, CLE | 2489 |
| 2. Noah Hass, DAL | 843 | |
| 3. Hunter Newberry, ATL | 341 | |
| 4. Noah Harden, HOU | 143 | |
| Rushing Yards | Complete List | |
Tre Durant
|
1. Tre Durant, NO | 1039 |
| 2. Ronnell Bowens, BUF | 1004 | |
| 3. John Blackburn, SEA | 589 | |
| 4. Deron Davis, TB | 360 | |
| 5. Terrance Gaston, ATL | 337 | |
| Receiving Yards | Complete List | |
LeVeon Huntley
|
1. LeVeon Huntley, DAL | 935 |
| 2. Darian Madison, SF | 836 | |
| 3. Kadron Loane, ATL | 809 | |
| 4. Glenn Way, WAS | 704 | |
| 5. Tre Durant, NO | 566 | |
League Leaders - Defense
| Tackles | Complete List | |
Michael Goodson
|
1. Michael Goodson, OAK | 47 |
| 2. Sean Cousins, PIT | 46 | |
| 3. Ilyaas Gooch, PHI | 40 | |
| 4. Luis Reese, HOU | 38 | |
| 5. Darrien Holly, CAR | 36 | |
| Sacks | Complete List | |
Jeffery Sorgi
|
1. Jeffery Sorgi, ATL | 12 |
| 2. Jamaan Smallwood, CHI | 8 | |
| 3. Garrod Hinton, BAL | 6 | |
| 4. Brandon Remmers, SF | 6 | |
| 5. Darrien Holly, CAR | 4 | |
| Interceptions | Complete List | |
Luis Reese
|
1. Luis Reese, HOU | 14 |
| 2. Martin Stanford, IND | 11 | |
| 3. Shanard Clement, LA | 6 | |
| 4. Sean Cousins, PIT | 4 | |
| 5. Michael Goodson, OAK | 4 | |
