League Leaders - Offense
| Passing Yards | Complete List | |
Tom Brady
|
1. Tom Brady, TB | 857 |
| 2. Aqeel Starks, PHI | 734 | |
| 3. Aaron Rodgers, GB | 674 | |
| 4. Brayden Sewell, DET | 645 | |
| 5. Joe Burrow, CIN | 636 | |
| Rushing Yards | Complete List | |
Rachaad White
|
1. Rachaad White, TEN | 341 |
| 2. Brian Robinson Jr, WAS | 252 | |
| 3. Saquon Barkley, NYG | 233 | |
| 4. Sheldon Samuels, CLS | 193 | |
| 5. Nick Chubb, CLE | 174 | |
| Receiving Yards | Complete List | |
Shelton Rowland
|
1. Shelton Rowland, TB | 428 |
| 2. Donovan Holcombe, WAS | 313 | |
| 3. Dallas Goedert, TB | 236 | |
| 4. Ja'Marr Chase, CIN | 232 | |
| 5. Devon Allen, NYG | 202 | |
League Leaders - Defense
| Tackles | Complete List | |
Jimmie Ward
|
1. Jimmie Ward, GB | 8 |
| 2. Cole Holcomb, WAS | 7 | |
| 3. Devin White, WAS | 7 | |
| 4. Zyon McCollum, TB | 7 | |
| 5. Khalan Tolson, BUF | 7 | |
| Sacks | Complete List | |
Chase Young
|
1. Chase Young, WAS | 4 |
| 2. Rashan Gary, GB | 4 | |
| 3. Deion Jones, ATL | 3 | |
| 4. Kyron Johnson, PHI | 3 | |
| 5. Von Miller, BUF | 2 | |
| Interceptions | Complete List | |
Trevon Diggs
|
1. Trevon Diggs, DAL | 4 |
| 2. Kevin Byard, TEN | 4 | |
| 3. Quandre Diggs, SEA | 3 | |
| 4. Jordan Fuller, LAR | 3 | |
| 5. Julian Blackmon, IND | 3 | |