League Leaders - Offense
| Passing Yards | Complete List | |
Lamar Jackson
|
1. Lamar Jackson, BAL | 1640 |
| 2. Kirk Cousins, MIN | 1429 | |
| 3. Trevor Lawrence, JAX | 1428 | |
| 4. Jordan Love, GB | 1349 | |
| 5. Aaron Rodgers, NYJ | 1293 | |
| Rushing Yards | Complete List | |
Jonathan Taylor
|
1. Jonathan Taylor, CIN | 722 |
| 2. Christian McCaffrey, SF | 702 | |
| 3. Joe Mixon, IND | 652 | |
| 4. Saquon Barkley, NYG | 599 | |
| 5. Derrick Henry, TEN | 593 | |
| Receiving Yards | Complete List | |
Alec Pierce
|
1. Alec Pierce, IND | 578 |
| 2. Rashod Bateman, BAL | 513 | |
| 3. Deebo Samuel, SF | 481 | |
| 4. A.J. Brown, PHI | 480 | |
| 5. Justin Jefferson, MIN | 478 | |
League Leaders - Defense
| Tackles | Complete List | |
Divine Deablo
|
1. Divine Deablo, LV | 21 |
| 2. Lavonte David, TB | 20 | |
| 3. Kyle Fuller, DEN | 20 | |
| 4. Zaven Collins, ARI | 20 | |
| 5. Jeremy Banks, BUF | 20 | |
| Sacks | Complete List | |
Kwity Paye
|
1. Kwity Paye, IND | 8 |
| 2. Trey Hendrickson, CIN | 8 | |
| 3. Danielle Hunter, MIN | 6 | |
| 4. Lukas Van Ness, GB | 6 | |
| 5. Nick Bosa, SF | 5 | |
| Interceptions | Complete List | |
Jabrill Peppers
|
1. Jabrill Peppers, NE | 5 |
| 2. Julian Blackmon, IND | 5 | |
| 3. Jessie Bates III, ATL | 5 | |
| 4. Mike Edwards, KC | 5 | |
| 5. Juan Thornhill, CLE | 5 | |