League Leaders - Offense
| Passing Yards | Complete List | |
D.J. Uiagalelei
|
1. D.J. Uiagalelei, CIN | 4692 |
| 2. Bryce Young, TEN | 3721 | |
| 3. Anthony Richardson, IND | 2947 | |
| 4. C.J. Stroud, NYG | 2416 | |
| 5. KJ Jefferson, SEA | 840 | |
| Rushing Yards | Complete List | |
Harold Joiner
|
1. Harold Joiner, CAR | 1330 |
| 2. Devon Achane, CHI | 946 | |
| 3. Jerome Ford, DET | 705 | |
| 4. Tank Bigsby, SEA | 666 | |
| 5. Zach Evans, ATL | 625 | |
| Receiving Yards | Complete List | |
Gary Bryant Jr.
|
1. Gary Bryant Jr., CIN | 1367 |
| 2. Kayshon Boutte, BAL | 1212 | |
| 3. Marvin Mims, NYJ | 1124 | |
| 4. Jaxon Smith-Njigba, CLE | 846 | |
| 5. Devon Achane, CHI | 816 | |
League Leaders - Defense
| Tackles | Complete List | |
Emmanuel Forbes
|
1. Emmanuel Forbes, BAL | 48 |
| 2. DJ Ivey, BAL | 46 | |
| 3. Eli Ricks, SF | 42 | |
| 4. Malachi Moore, TB | 42 | |
| 5. Kelee Ringo, MIN | 42 | |
| Sacks | Complete List | |
Byron Young
|
1. Byron Young, IND | 7 |
| 2. Jaquelin Roy, DEN | 7 | |
| 3. J.D. Bertrand, DET | 6 | |
| 4. Bryan Bresee, HOU | 6 | |
| 5. Storm Duck, MIA | 5 | |
| Interceptions | Complete List | |
Kei'Trel Clark
|
1. Kei'Trel Clark, KC | 9 |
| 2. Cam Smith, IND | 7 | |
| 3. Eli Ricks, SF | 6 | |
| 4. Tony Grimes, KC | 6 | |
| 5. Antonio Johnson, CHI | 6 | |